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Just how much of a challenge this posed can be gauged from the fact that Mutt's group needed 10km of porcine small intestine to obtain about 1mg of pure secretin (Rehfeld 2012)
Hunger hormones rebound
26 , 620632.e6 (2017)
It plays a crucial role in helping reduce oxidative stress by neutralizing free radicals that can damage cells and accelerate aging
Additional reference Lei L and Liu Y
That means you're measuring your own dose with a syringe - and the concentration per milliliter on a compounded vial can differ from what you'd expect if you're used to auto-injectors
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